UQ Holder!: Mahou Sensei Negima! 2

In the decade since the world became aware of the existence of magic, the world has undergone massive upheaval. However, a boy named Touta lives in seclusion in a rural town far removed from these changes. His ordinary life is highlighted by his magic-using female teacher and his supportive friends. When his tranquil daily life is disrupted, he embarks on a unique adventure.

(Source: Anime News Network)